Nora Ephron, a legend in the Hollywood circles and the screenwriter of some of the most heralded romantic comedies of all-time, has died, TMZ is reporting.

Ephron, who penned "Sleepless in Seattle," "When Harry Met Sally," "You've Got Mail," "Julie and Julia" and "Michael," among many others, died of cancer.

TMZ reported earlier Ephron had been gravely ill from the disease. Ephron was married three times, once to famed Washington Post reporter Carl Bernstein, who helped uncover Richard Nixon's Watergate scandal.

Thoughts and prayers to Ephron's friends and family.